Saturday 20 October 2012

ScienceDaily: Latest Science News

ScienceDaily: Latest Science News


Cholera discovery could revolutionize antibiotic delivery

Posted: 19 Oct 2012 12:32 PM PDT

Scientists have made a discovery that could help revolutionize antibiotic treatment of deadly bacteria. They have explained how Vibrio cholerae became a deadly pathogen thousands of years ago. Two genes within V. cholerae's genome make it toxic and deadly. The bacterium acquired these genes when a bacterial virus or bacteriophage called CTX-phi infected it.

Researchers explore how the brain perceives direction and location

Posted: 19 Oct 2012 12:32 PM PDT

Neurobiologists have studied the activity of special brain cells that make possible spatial navigation -- the process by which you establish where "here" is and how you get from here to "there."

Science reveals the power of a handshake

Posted: 19 Oct 2012 11:13 AM PDT

New neuroscience research is confirming an old adage about the power of a handshake: strangers do form a better impression of those who proffer their hand in greeting.

Daily vibration may combat prediabetes in youth

Posted: 19 Oct 2012 11:12 AM PDT

Daily sessions of whole-body vibration may combat prediabetes in adolescents. In mice that mimic over-eating adolescents headed toward diabetes, 20 minutes of daily vibration for eight weeks restored a healthy balance of key pro- and anti-inflammatory mediators and was better than prescription drugs at reducing levels of hemoglobin A1c, the most accurate indicator of average blood glucose levels, according to new research.

Take control: Exploring how self-discipline works and how we might boost it

Posted: 19 Oct 2012 11:12 AM PDT

Self-control helps us keep our cool, get things done, and resist the things that tempt us. Numerous studies have found evidence for the idea of self-control as a limited resource, but emerging research suggests that this model may not tell the whole story. New research explores the various mechanisms -- metabolic, cognitive, motivational, affective -- thought to underlie self-control.

Breakthrough offers new route to large-scale quantum computing

Posted: 19 Oct 2012 11:12 AM PDT

In a key step toward creating a working quantum computer, researchers have developed a method that may allow the quick and reliable transfer of quantum information throughout a computing device.

Weight loss does not lower heart disease risk from type 2 diabetes, study suggests

Posted: 19 Oct 2012 11:12 AM PDT

An intensive diet and exercise program resulting in weight loss does not reduce cardiovascular events such as heart attack and stroke in people with longstanding type 2 diabetes, according to a new study.

Pediatric studies show the flu's deadly danger, the benefits of school vaccinations

Posted: 19 Oct 2012 11:12 AM PDT

New data shows the fatal risk that influenza poses even for children without underlying health conditions and the effectiveness of school-based vaccination programs in protecting student populations. Together, these findings support the crucial public health message that families should take the flu virus seriously every year.

Plant-based foods may offer reduced risk for aggressive prostate cancer

Posted: 19 Oct 2012 11:11 AM PDT

A new study finds that a high intake of flavonoids, a group of compounds found in plants, may lower the risk for highly aggressive prostate cancer.

Key player in Parkinson's disease neuron loss pinpointed

Posted: 19 Oct 2012 11:11 AM PDT

By reprogramming skin cells from Parkinson's disease patients with a known genetic mutation, researchers have identified damage to neural stem cells as a powerful player in the disease. The findings may lead to new ways to diagnose and treat the disease.

Attention deficit hyperactivity disorder is both under and over diagnosed, study suggests

Posted: 19 Oct 2012 11:11 AM PDT

Scientists have completed one of the largest studies on ADHD in the United States. The study shows that ADHD is both under and over diagnosed, a finding with important implications for both prevalence and treatment needs.

Astronomers uncover a surprising trend in galaxy evolution

Posted: 19 Oct 2012 10:54 AM PDT

A comprehensive study of hundreds of galaxies observed by the Keck telescopes in Hawaii and NASA's Hubble Space Telescope has revealed an unexpected pattern of change that extends back 8 billion years, or more than half the age of the universe.

Recession drives down U.S. national park visitation

Posted: 19 Oct 2012 10:06 AM PDT

A national recession doesn't just affect Americans' wallets. It also impacts their travel to national parks, a new study has found. Recent visitation statistics released by the US Department of Interior already noted the significant decrease in national park visitation -- dropping nearly 10 million since 1998 to 278 million visitors -- but this is the first study to link the drop to a bad economy.

Beneficial mold packaged in bioplastic

Posted: 19 Oct 2012 10:06 AM PDT

Aflatoxins are highly toxic carcinogens produced by several species of Aspergillus fungi. But not all Aspergillus produce aflatoxin. Some, in fact, are considered beneficial. One such strain, dubbed K49, is now being recruited to battle these harmful Aspergillus relatives, preventing them from contaminating host crops like corn with the carcinogen. Scientists have now devised a new method of applying K49 as a frontline defense against aflatoxin contamination in corn.

Studies target high rates of HIV medication errors among hospitalized patients

Posted: 19 Oct 2012 10:05 AM PDT

New research concludes that despite advances in electronic medical records, mistakes are still commonly made in the prescription of antiretroviral medications for hospitalized HIV-positive patients. At the same time, a trio of studies suggests however, that electronic records in combination with increased clinical education can help to greatly decrease medical errors.

Cell mechanism findings could one day be used to engineer organs

Posted: 19 Oct 2012 10:05 AM PDT

Biologists have teamed up with mechanical engineers to conduct cell research that provides information that may one day be used to engineer organs.

Bowhead whales: Ancient DNA sheds light on Arctic whale mysteries

Posted: 19 Oct 2012 10:05 AM PDT

Scientists have published the first range-wide genetic analysis of the bowhead whale using hundreds of samples from both modern populations and archaeological sites used by indigenous Arctic hunters thousands of years ago.

World's largest earthquake drill: JPL scientists participate in Great California ShakeOut exercises

Posted: 19 Oct 2012 08:48 AM PDT

On Thursday, Oct. 18, at 10:18 a.m. PDT, more than 9.3 million Californians, including employees at NASA's Jet Propulsion Laboratory, Pasadena, Calif., "dropped, covered and held on" during the 5th annual Great California ShakeOut, the world's largest earthquake drill. The purpose of the ShakeOut is to encourage people and organizations to be prepared to survive and recover when the next big earthquake happens.

NASA's Kennedy Space Center supporting effort to develop satellite servicing capabilities

Posted: 19 Oct 2012 08:45 AM PDT

With satellites playing increasingly important roles in everyday life, NASA is developing the technology to build Earth-orbiting, roving "service stations" capable of extending the life of these spacecraft. Engineers at the Kennedy Space Center in Florida are assisting the space agency's Goddard Space Flight Center in Greenbelt, Md., in developing the concept for bringing a high-technology gas pump, robotic mechanic and tow truck to satellites in space.

NASA C-20A completes radar study of Pacific Rim volcanoes

Posted: 19 Oct 2012 08:44 AM PDT

NASA's Airborne Science C-20A aircraft, carrying a specialized synthetic aperture radar, recently completed a mission to study active volcanoes in Alaska, Aleutian Islands and Japan in early October. The aircraft, a modified version of the Gulfstream III business jet, made 10 flights totaling more than 50 hours during the eight-day campaign. The Uninhabited Aerial Vehicle Synthetic Aperture Radar (UAVSAR), developed and operated by NASA's Jet Propulsion Laboratory, collected 60 of 61 planned data lines.

Hubble sees galaxy in a spin

Posted: 19 Oct 2012 08:42 AM PDT

NGC 3344 is a glorious spiral galaxy around half the size of the Milky Way, which lies 25 million light-years distant. We are fortunate enough to see NGC 3344 face-on, allowing us to study its structure in detail.

Mars soil sample delivered for analysis inside rover

Posted: 19 Oct 2012 08:38 AM PDT

NASA's Mars rover Curiosity has ingested its first solid sample into an analytical instrument inside the rover, a capability at the core of the two-year mission.

How to prove a sexual addiction: Criteria for diagnosing 'hypersexual disorder' tested

Posted: 19 Oct 2012 07:28 AM PDT

Experts have tested a proposed set of criteria to define "Hypersexual Disorder" (HD), as a new mental health condition, and found the proposed criteria to be reliable and valid. The results will influence whether HD should be included in the forthcoming revised fifth edition of the Diagnostic and Statistical Manual of Mental Disorders considered the "bible" of psychiatry.

Goodness, gracious, great balls of lightning!

Posted: 19 Oct 2012 07:28 AM PDT

Australian scientists have unveiled a new theory which explains the mysterious phenomenon known as ball lightning.

Young people who go out drinking start earlier and consume more and more alcohol

Posted: 19 Oct 2012 07:27 AM PDT

Teenagers and university students are unaware of the negative consequences of alcohol consumption or the chances of developing an addiction as a result. In addition, they start at a younger and younger age and drink more and stronger alcohol according to a new study.

Obama has better leadership skills, survey shows

Posted: 19 Oct 2012 07:26 AM PDT

A new survey that evaluated the leadership skills of President Barack Obama and Republican challenger Mitt Romney has found that Obama scored significantly better than Romney in most leadership categories and in overall leadership skill.

Foster kids do equally well when adopted by gay, lesbian or heterosexual parents, study suggests

Posted: 19 Oct 2012 06:45 AM PDT

High-risk children adopted from foster care do equally well when placed with gay, lesbian and heterosexual parents, psychologists report.

Solar power used to study elephants in Africa

Posted: 19 Oct 2012 06:45 AM PDT

A team of elephant researchers has transformed a remote corner of southern Africa into a high-tech field camp run entirely on sunlight. The seasonal solar-powered research camp gives scientists a rare opportunity to quietly observe, videotape and photograph wild elephants at Mushara waterhole, an isolated oasis in Etosha National Park in Namibia.

Forest fires linked to high temperatures two years before

Posted: 19 Oct 2012 06:45 AM PDT

Researchers analyzed the impact of interannual and seasonal climate variability on the fires occurred in Catalonia, Spain, last summer. The study concludes that summer fires, related to summer climate conditions, are correlated with antecedent climate conditions, especially winter and spring ones with a lag time of two years. The results suggest that precipitation and temperature conditions regulate fuel flammability and fuel structure. According to the correlations observed, the study provides a model to produce long-term predictions.

Measuring women's risk of osteoporosis

Posted: 19 Oct 2012 06:29 AM PDT

For women of mixed racial or ethnic backgrounds, a new method for measuring bone health may improve the odds of correctly diagnosing their risk of osteoporosis and bone fractures.

Debate reactions measured in real time

Posted: 19 Oct 2012 06:29 AM PDT

Researchers are measuring audience reactions to the debates live, second-by-second, using state-of-the-art technology. For the final debate, they will have people from the community participate. The research center will have 10 Republicans and 10 Democrats, a mix of men and women, watch and rate the debate performance in real time.

How the brain forms categories

Posted: 19 Oct 2012 06:29 AM PDT

Neurobiologists have investigated how the brain is able to group external stimuli into stable categories. They found the answer in the discrete dynamics of neuronal circuits.

Presidential debates offer body language tips for job interviews

Posted: 19 Oct 2012 06:29 AM PDT

Considering President Barack Obama and GOP nominee Mitt Romney are seeking the nation's top job, watching Monday's Presidential debate could be just the prep needed to ace your next job interview. While pointing fingers, interrupting and smirking are never recommended in a professional setting, job seekers can learn a lot from the candidates' speech and body language.

Sharp rise in children admitted to hospital with throat infections since 1999

Posted: 19 Oct 2012 05:21 AM PDT

The number of children admitted to hospital in England for acute throat infections increased by 76 per cent between 1999 and 2010, according to new research.

Deciphering the first epigenomes of chronic lymphocytic leukemia

Posted: 19 Oct 2012 05:21 AM PDT

Researchers have deciphered the first epigenomes of chronic lymphocytic leukemia.

First micro-structure atlas of human brain completed

Posted: 19 Oct 2012 05:21 AM PDT

Scientists have built the first atlas of white-matter microstructure in the human brain. The project's final results have the potential to change the face of neuroscience and medicine over the coming decade.

No survival advantage with peripheral blood stem cells versus bone marrow, study suggests

Posted: 19 Oct 2012 04:15 AM PDT

Medical researchers conducted a two-year clinical trial comparing two-year survival probabilities for patients transplanted with peripheral blood stem cells or bone marrow stem cells from unrelated donors.

Common risky behaviors of children struck by motor vehicles outlined

Posted: 19 Oct 2012 04:15 AM PDT

Pediatricians have outlined the risky behavior of child pedestrians who are struck by cars -- including darting into the street, crossing in the middle of the block, and crossing while using an electronic device.

Few teens undergo pregnancy testing in emergency department

Posted: 19 Oct 2012 04:15 AM PDT

Few adolescent females undergo pregnancy testing in the hospital emergency department, even when they complain of lower abdominal pain, or before they are exposed to radiation for tests or examinations, according to a new study.

Collective violence and poverty on the Mexican-US border affects child mental health

Posted: 19 Oct 2012 04:15 AM PDT

Collective violence attributed to organized crime and poverty are adversely affecting the mental health of children living near the Texas-Mexico border, according to new research.

Fast image processing developed for industry

Posted: 19 Oct 2012 04:14 AM PDT

The mining and steel industries, as well as the aggregates industry that produces rock and stone for construction and industry needs, were the focus end-users for new fast image analysis capabilities for measurement feedback in industry processes. Researchers have developed LTU-CUDA, a software for fast image processing based on high performance graphics cards commonly found in today's personal computers.

A sharper look into the past for archaeology and climate research

Posted: 19 Oct 2012 04:14 AM PDT

By using a new series of measurements of radiocarbon dates on seasonally laminated sediments from Lake Suigetsu in Japan, a more precise calibration of radiocarbon dating will be possible. In combination with an accurate count of the seasonal layered deposits in the lake, the study resulted in an unprecedented precision of the known 14C method with which it is now possible to date older objects of climate research and archeology more precisely than previously achievable.

Evolution: New understandings of how populations change over time

Posted: 19 Oct 2012 04:14 AM PDT

Since 1859, when Darwin's classic work "On the Origin of Species" was published, we have known that populations change over the course of time.  The ability to adapt to changing surroundings is the basis for evolution and is crucial for animals and plants to come to terms with new environmental conditions, for example as a consequence of climate change.  Despite the obvious importance of the process, however, we still do not understand the underlying mechanisms.  It is clear that organisms change their DNA in response to selection pressures.  But how? 

Pristine Maksimjärvensalo wilderness area remains in Republic of Karelia

Posted: 19 Oct 2012 04:14 AM PDT

Maksimjärvensalo, situated south of the Kostamus Strict Nature Reserve, is a wilderness area unaffected by loggings, thus being an important part of the Green Belt of Fennoscandia. A proposal has been made to protect it as part of the GAP analysis development project of the protected area network in Northwest Russia. Many observations of polypores, lichens and bryophytes threatened in Finland have been made in the area. Some of these species are classified as threatened in Karelia, as well. The continuous forested wilderness area also provides an important habitat for the forest reindeer (Rangifer tarandus fennicus) whose populations have declined rapidly in Karelia.

Low calcium diet linked to higher risk of hormone condition in women

Posted: 18 Oct 2012 03:59 PM PDT

A low calcium diet is associated with a higher risk of developing a common hormone condition in women, known as primary hyperparathyroidism, a new study suggests.

Possibilities, challenges, and applications of next-generation sequencing

Posted: 18 Oct 2012 01:20 PM PDT

A report provides a detailed and compelling overview of the landscape of next generation sequencing (NGS) technology and its clinical relevance and impact on improving patient care.

Friday 19 October 2012

ScienceDaily: Latest Science News

ScienceDaily: Latest Science News


What we know and don't know about fungal meningitis outbreak

Posted: 18 Oct 2012 03:59 PM PDT

In a new perspective piece, a physician recalls lessons learned from treating patients affected by the 2002 outbreak of Exophiala (Wangiella) dermatitidis meningitis or arthritis related to contaminated, injectable coticosteroids prepared from a compounding pharmacy.

Poetry in motion: Gemini Observatory releases image of rare polar ring galaxy

Posted: 18 Oct 2012 03:59 PM PDT

Polar-ring galaxies are peculiar objects. Astronomers have found only a handful of them, so not much is known about their origins. Most have an early-type spiral system, called a lenticular galaxy, as the central showpiece. But NGC 660, which lies about 40 million light-years distant toward the direction of Pisces the Fishes, is the only polar-ring galaxy known with what is called a late-type lenticular galaxy as its host. All, however, display a ring of stars, dust, and gas that extends tens of thousands of light-years across space along an orbit nearly perpendicular to the main disk.

NASA pursues atom optics to detect the imperceptible

Posted: 18 Oct 2012 03:59 PM PDT

A pioneering technology capable of atomic-level precision is now being developed to detect what so far has remained imperceptible: gravitational waves or ripples in space-time caused by cataclysmic events including even the Big Bang itself.

The hidden burden of bovine Tuberculosis

Posted: 18 Oct 2012 03:59 PM PDT

Up to 21 percent of herds clearing restrictions for bovine Tuberculosis (bTB) in Great Britain may be harbouring infection, according to a new study.

Tissue-engineered kidneys: Researchers make important strides

Posted: 18 Oct 2012 03:48 PM PDT

With a worldwide shortage of kidneys for patients who need kidney transplants, researchers are diligently working to find ways to engineer new kidney tissue from a patient's own cells or another source. They've come a step closer to realizing that goal with a breakthrough described in a new study. The advance could lead to more options for individuals with kidney failure, as well as better tools for understanding kidney diseases and how to treat them.

Damage to blood vessel lining may account for kidney failure patients' heart risks

Posted: 18 Oct 2012 03:48 PM PDT

Individuals with kidney failure often develop heart problems, but it's not clear why. A new study provides evidence that their kidneys' inability to excrete waste products in the urine, which leads to build-up of these products in the blood, may damage the sugary lining of blood vessels and lead to heart troubles.

New way to save blood from ravages of chemo treatment

Posted: 18 Oct 2012 01:26 PM PDT

Chemotherapy kills blood cells as well as cancer cells, often with fatal results. Now stem cell researchers have identified a method they hope one day will help cancer patients undergoing chemotherapy maintain a healthy blood supply, they report.

Solar power is contagious

Posted: 18 Oct 2012 01:22 PM PDT

People are more likely to install a solar panel on their home if their neighbors have one, according to a new study. The researchers studied clusters of solar installations throughout California from January 2001 to December 2011 and found that residents of a particular zip code are more likely to install solar panels if they already exist in that zip code and on their street.

First-of-its-kind self-assembled nanoparticle for targeted and triggered thermo-chemotherapy

Posted: 18 Oct 2012 01:22 PM PDT

Researchers describe the design and effectiveness of a first-of-its-kind, self assembled, multi-functional, NIR responsive gold nanorods that delivers a chemotherapy drug specifically targeted to cancer cells and selectively release the drug in response to an external beam of light while creating heat for synergistic thermo-chemo mediated anti-tumor efficacy.

Bicycle infrastructure can reduce risk of cycling injuries by half, Canadian study finds

Posted: 18 Oct 2012 01:22 PM PDT

Certain types of routes carry much lower risk of injury for cyclists, according to a new study. The study analyzed the cause of 690 cycling injuries in Vancouver and Toronto from 2008 to 2009 and various route types and infrastructure.

Living in ethnically homogenous area boosts health of minority seniors, study finds

Posted: 18 Oct 2012 01:22 PM PDT

An African-American or Mexican-American senior living in a community where many neighbors share their background is less likely to have cancer or heart disease than their counterpart in a more mixed neighborhood, according to a new study.

Child's home address helps predict risk of readmission to hospital

Posted: 18 Oct 2012 01:22 PM PDT

Simply knowing a child's home address and some socioeconomic data can serve as a vital sign -- helping hospitals predict which children admitted for asthma treatment are at greater risk for re-hospitalization or additional emergency room visits, according to new research.

Study succeeds in cutting inappropriate antibiotic prescribing by pediatricians

Posted: 18 Oct 2012 01:22 PM PDT

A study involving one of the nation's largest networks of pediatric practices was able to nearly halve the inappropriate use of antibiotics through quarterly monitoring and feedback of the physicians' prescribing patterns. The research is one of the first to look at an antimicrobial stewardship intervention in the outpatient setting.

Hospital uses ‘lean’ manufacturing techniques to speed stroke care

Posted: 18 Oct 2012 01:20 PM PDT

A hospital stroke team used auto industry "lean" manufacturing principles to accelerate treatment times, according to new research.

Stroke patients benefit from carmaker’s efficiency

Posted: 18 Oct 2012 01:20 PM PDT

A process developed to increase efficiency and productivity in Japanese car factories has helped improve stroke treatment at Barnes-Jewish Hospital in St. Louis, Missouri.

Salt power: Watt's next in rechargeable batteries?

Posted: 18 Oct 2012 12:19 PM PDT

Sodium could be an effective, inexpensive and virtually inexhaustible substitute for lithium, but it has a drawback that researchers hope to address.

Mechanisms of action for green tea extract in breast cancer prevention identified

Posted: 18 Oct 2012 12:19 PM PDT

An oral green tea extract, Polyphenon E, appears to inhibit vascular endothelial growth factor and hepatocyte growth factor, both of which promote tumor cell growth, migration and invasion.

Blood hormone levels predicted long-term breast cancer risk for postmenopausal women

Posted: 18 Oct 2012 12:19 PM PDT

Blood hormone tests predicted a woman's risk for developing postmenopausal breast cancer for up to 20 years, according to new research.

Team support for cessation in the workplace helped motivate cigarette smokers to quit

Posted: 18 Oct 2012 12:19 PM PDT

When smoking co-workers in the same team are placed on a cessation program, providing financial incentives to the team collectively in return for success of the smokers in the cessation program helped the smokers to quit smoking and remain abstinent for 12 months, according to new research.

High levels of estradiol, progesterone during pregnancy associated with increased risk for HR-negative breast cancer

Posted: 18 Oct 2012 12:19 PM PDT

Increased concentrations of the pregnancy hormones estradiol and progesterone were associated with an increased risk for hormone receptor-negative breast cancer diagnosed before age 50, according to the results of a nested case-control study.

Depression, shortened telomeres increase mortality in bladder cancer patients

Posted: 18 Oct 2012 11:18 AM PDT

Low depressive symptoms and a longer telomere length are compelling factors that contribute to a prolonged life for bladder cancer patients, according to researchers.

Modeling feat sheds light on protein channel's function

Posted: 18 Oct 2012 11:18 AM PDT

Chemists have managed, for the first time, to simulate the biological function of a channel called the Sec translocon, which allows specific proteins to pass through membranes. The feat required bridging timescales from the realm of nanoseconds all the way up to full minutes, exceeding the scope of earlier simulation efforts by more than six orders of magnitude. The result is a detailed molecular understanding of how the translocon works.

Elevated risk of blood clots in women taking birth control containing drospirenone, study shows

Posted: 18 Oct 2012 11:18 AM PDT

New research has found an increased risk of arterial thrombotic events and venous thromboembolic events -- commonly referred to as blockage of arteries and blood clots, respectively -- associated with drospirenone-containing birth control pills compared to four low-dose estrogen combined hormonal contraceptives.

Tropical collapse in Early Triassic caused by lethal heat: Extreme temperatures blamed for 'Dead Zone'

Posted: 18 Oct 2012 11:18 AM PDT

Scientists have discovered why the 'broken world' following the worst extinction of all time lasted so long -- it was simply too hot to survive. The end-Permian mass extinction, which occurred around 250 million years ago in the pre-dinosaur era, wiped out nearly all the world's species. Typically, a mass extinction is followed by a 'dead zone' during which new species are not seen for tens of thousands of years. In this case, the dead zone, during the Early Triassic period which followed, lasted for a perplexingly long period: five million years.

New technique for nanostructure assembly pioneered

Posted: 18 Oct 2012 11:18 AM PDT

A team of researchers has developed a new technique for growing new materials from nanorods. Materials with enhanced properties engineered from nanostructures have the potential to revolutionize the marketplace in everything from data processing to human medicine. However, attempts to assemble nanoscale objects into sophisticated structures have been largely unsuccessful. This latest study represents a major breakthrough in the field, showing how thermodynamic forces can be used to manipulate growth of nanoparticles into superparticles with unprecedented precision.

Optical vortices on a chip: Integrated arrays of emitters of 'optical vortex beams' on a silicon chip

Posted: 18 Oct 2012 11:18 AM PDT

Researchers have demonstrated integrated arrays of emitters of 'optical vortex beams' on a silicon chip. Contradicting traditional conception, light in such beams does not propagate in straight rays. Instead, its energy travels in a spiral fashion in a hollow conical beam shape. The beams therefore look very much like a vortex or cyclone, with its light rays 'twisted' either left-handed or right-handed. In theory, there is no limit to how twisted the light rays can be.

Researchers unveil 3-D structure of 'molecular machine' that initiates DNA transcription

Posted: 18 Oct 2012 11:18 AM PDT

Scientists have determined the three-dimensional structure of the transcription initiation complex, the key intermediate in the process by which cells read out genetic information in DNA. The "molecular machine" responsible for transcription initiation -- a protein complex that consists of the enzyme RNA polymerase and the initiation factor sigma -- recognizes a specific site on DNA preceding a gene, binds to DNA, unwinds the DNA helix, and pre-organizes the unwound DNA to enable subsequent reactions.

'Time-capsule' Japanese lake sediment advances radiocarbon dating for older objects

Posted: 18 Oct 2012 11:18 AM PDT

A series of radiocarbon measurements from Japan's Lake Suigetsu will give scientists a more accurate benchmark for dating materials, especially for older objects. Researchers extracted cores containing organic material from the bottom of the Japanese lake where it had lain undisturbed for tens of thousands of years. They provide a more precise way to examine radiocarbon ages of organic material for the entire 11,000-53,000-year time range.

No antibodies, no problem: Researchers identify how mosquito immune system attacks specific infections

Posted: 18 Oct 2012 10:40 AM PDT

Researchers have determined a new mechanism by which the mosquitoes' immune system can respond with specificity to infections with various pathogens, including the parasite that causes malaria in humans, using one single gene. Unlike humans and other animals, insects do not make antibodies to target specific infections.

Rejection bolsters creativity: Independent individuals can benefit from exclusion

Posted: 18 Oct 2012 10:39 AM PDT

Social rejects can be tomorrow's innovators because being an outcast can lead to heightened creativity and even commercial success, according to researchers.

Election 2012: Will voters follow their 'gut feelings' at polls?

Posted: 18 Oct 2012 10:39 AM PDT

Americans going to the polls generally pull the lever based on one thing: their gut feelings, says a presidential politics expert.

Technology has improved voting procedures

Posted: 18 Oct 2012 10:09 AM PDT

Thanks to better voting technology over the last decade, the country's election process has seen much improvement, according to a new report. However, the report notes, despite this progress, some problems remain.

Germs in space: Preventing infection on long flights

Posted: 18 Oct 2012 10:09 AM PDT

On a long spaceflight unique conditions including microgravity could give microbes the upper hand, but not if astronauts and their spacecrafts are properly prepared. Infectious disease experts have come up with specific recommendations for keeping astronauts safe in deeper space.

Norovirus outbreaks in nursing homes associated with increase in hospitalizations, risk of death

Posted: 18 Oct 2012 10:09 AM PDT

In a study that included more than 300 Medicare-certified nursing homes, rates of hospitalization and death were substantially increased during outbreaks of norovirus gastroenteritis vs. non-outbreak periods.

Ultraviolet light effective in hospital infection control, study suggests

Posted: 18 Oct 2012 10:09 AM PDT

A specific spectrum of ultraviolet light killed certain drug-resistant bacteria on the door handles, bedside tables and other surfaces of hospital rooms, suggesting a possible future weapon in the battle to reduce hospital-associated infections.

Prehistoric human populations prospered before the agricultural boom, research suggests

Posted: 18 Oct 2012 10:08 AM PDT

Researchers have found major prehistoric human population expansions may have begun before the Neolithic period, which probably led to the introduction of agriculture.

NASA's Global Precipitation Measurement observatory completes first dry run

Posted: 18 Oct 2012 09:48 AM PDT

NASA's Global Precipitation Measurement (GPM) Core Observatory satellite went through its first complete comprehensive performance test (CPT), beginning on Oct. 4, 2012 at NASA's Goddard Space Flight Center in Greenbelt, Md. The testing ran twenty-four hours, seven days a week and lasted ten days as the entire spacecraft was put through its paces.

Reprogrammed amniotic fluid cells could treat vascular diseases

Posted: 18 Oct 2012 09:33 AM PDT

Scientists have discovered a way to utilize diagnostic prenatal amniocentesis cells, reprogramming them into abundant and stable endothelial cells capable of regenerating damaged blood vessels and repairing injured organs.

Developed a technology that predicts metastasis in breast cancer

Posted: 18 Oct 2012 09:33 AM PDT

Researchers have developed a diagnostic tool that identifies the metastatic ability of breast cancer cells. The analysis is based on the characterization of the lipid component of the cells, which is indicative of malignancy.

Mutation that causes skin hyperproliferation identified

Posted: 18 Oct 2012 09:33 AM PDT

Scientists have identified a mutation in a gene that causes patches of very thick skin to appear on the palms and soles of affected people. This skin disorder is related, albeit in a much milder form, to that of the Indonesian "Tree Man", Dede Koswara.

Ozone affects forest watersheds

Posted: 18 Oct 2012 09:33 AM PDT

Scientists have found that rising levels of ozone, a greenhouse gas, may amplify the impacts of higher temperatures and reduce streamflow from forests to rivers, streams, and other water bodies. Such effects could potentially reduce water supplies available to support forest ecosystems and people in the southeastern United States.

Cancer diagnosis does not make young people religious, research suggests

Posted: 18 Oct 2012 09:30 AM PDT

A sociologist of religion has interviewed 21 young patients diagnosed with a life-threatening cancer about their religious beliefs. She concludes that a cancer diagnosis will not make young people, who are not religious already, turn to religion. But it can confirm already existing beliefs.

College students and credit card debt: Parents have a powerful influence on their children's financial behaviors

Posted: 18 Oct 2012 09:30 AM PDT

Parents need to be good role models to help their children make sensible financial decisions, according to researchers whose work highlights that parents who argue about finances contribute to increasing credit card debt among their children during their student years.

Female Pulitzer Prize winners require higher qualifications, study finds

Posted: 18 Oct 2012 09:30 AM PDT

A researcher has found that female Pulitzer Prize winners are more likely to have greater qualifications their male counterparts in order to win the coveted award.

Genes and immune system shaped by childhood poverty, stress

Posted: 18 Oct 2012 09:30 AM PDT

New research has revealed that childhood poverty, stress as an adult, and demographics such as age, sex and ethnicity, all leave an imprint on a person's genes. And, that this imprint could play a role in our immune response.

Scientists harness immune system to prevent lymphoma relapse

Posted: 18 Oct 2012 09:30 AM PDT

Scientists hope that lymphoma patients could benefit from a new drug that triggers the cancer-fighting properties of the body's own immune system, after highly promising early laboratory results.

Researchers elucidate transport pathway of immune system substances

Posted: 18 Oct 2012 09:30 AM PDT

To transport substances from the site of their production to their destination, the body needs a sophisticated transport and sorting system. Various receptors in and on the cells recognize certain molecules, pack them and ensure that they are transported to the right place. One of these receptors is Sortilin. It is present in the cells of the nervous system, the liver, and the immune system. Studies have now shown that the receptor Sortilin plays an important role in the function of the immune system.

Rethinking toxic proteins on the cellular level: Lipid droplets play an unexpected role in embryo development

Posted: 18 Oct 2012 09:30 AM PDT

Histones are proteins needed to assemble DNA molecules into chromosomes. They have long represented a classic balancing act in biology; too few histone molecules result in DNA damage, while too many histones are toxic to the cell. New research is causing a fundamental shift in the concept of histone balance and the mechanism behind it.

Treating vascular disorders with a cell-based strategy

Posted: 18 Oct 2012 09:30 AM PDT

A new approach for generating large numbers of circulatory system cells, known as vascular endothelial cells (VECs), from human amniotic-fluid-derived cells is reported in a new study. The strategy, which shows promise in mice, opens the door to establishing a vast inventory of VECs for promoting organ regeneration and treating diverse vascular disorders.

From the twitching whiskers of babes: Naptime behavior shapes the brain

Posted: 18 Oct 2012 09:30 AM PDT

The whiskers of newborn rats twitch as they sleep, in a whisker equivalent of rapid-eye-movements, and that could open the door to new understandings about the intimate connections between brain and body. The discovery reinforces the notion that such involuntary movements are a vital contributor to the development of sensorimotor systems, say researchers.

Super rats are immune to conventional poisons, UK experts find

Posted: 18 Oct 2012 09:28 AM PDT

Scientists in the United Kingdom have noticed a mounting problem of destructive "super rats" immune to conventional poison.

Value of combined approach to quitting smoking confirmed

Posted: 18 Oct 2012 09:20 AM PDT

Smokers who try to quit would be more successful if they combined medication or nicotine-replacement therapy with behavioral counseling, finds a new review.

Breast-feeding reduced risk for ER/PR-negative breast cancer, results find

Posted: 18 Oct 2012 09:19 AM PDT

Breast-feeding reduced the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to new results.

Green tea reduced inflammation, may inhibit prostate cancer tumor growth, research finds

Posted: 18 Oct 2012 09:19 AM PDT

Men with prostate cancer who consumed green tea prior to undergoing prostatectomy had reductions in markers of inflammation, according to new data

Compound's dual action inhibited oral cancer, rat study finds

Posted: 18 Oct 2012 09:19 AM PDT

The compound licofelone inhibited oral cancer growth by inhibiting the cyclooxygenase and 5-lipoxygenase pathways, with no observable side effects, according to a recent rat study.

Hay fever, asthma combination linked to lower risk for death from colorectal cancer, study finds

Posted: 18 Oct 2012 09:19 AM PDT

People with both hay fever and asthma -- but not people with only one of these two conditions -- experienced an approximately 17 percent lower risk for dying from colorectal cancer, according to new research.

Could a hurricane ever strike Southern California?

Posted: 18 Oct 2012 07:57 AM PDT

There's an old adage (with several variations) that California has four seasons: earthquake, fire, flood and drought. While Californians happily cede the title of Hurricane Capital of America to U.S. East and Gulf coasters, every once in a while, Mother Nature sends a reminder to Southern Californians that they are not completely immune to the whims of tropical cyclones. Typically, this takes the form of rainfall from the remnants of a tropical cyclone in the eastern Pacific, as happened recently when the remnants of Hurricane John brought rain and thunderstorms to parts of Southern California. But could a hurricane ever make landfall in Southern California?

Supersonic model points to fast future

Posted: 18 Oct 2012 07:53 AM PDT

If human beings are ever to fly faster than the speed of sound from one side of the country to another, we first have to figure out how to reduce the level of sonic boom generated by supersonic flight. Earlier this fall, a subscale model of a potential future low-boom supersonic aircraft designed by The Boeing Company was installed for testing in the supersonic wind tunnel at NASA's Glenn Research Center in Cleveland.

Space Launch System providing engine 'brains' with an upgrade

Posted: 18 Oct 2012 07:50 AM PDT

America's next heavy-lift rocket needs a strong and reliable engine to launch humans beyond low Earth orbit. That's why engineers with NASA's Space Launch System program, managed at the Marshall Space Flight Center in Huntsville, Ala., will use the proven RS-25, the space shuttle's main engine during its 30-year history, to power the massive rocket's core stage. The RS-25, which was designed and developed with NASA by Pratt & Whitney Rocketdyne of Canoga Park, Calif., is a crucial part to the core stage design, but a few enhancements are planned.

Aggressive nature of meningitis cases calls for heightened awareness among clinicians

Posted: 18 Oct 2012 07:32 AM PDT

More than 200 patients have been diagnosed with fungal meningitis following spinal epidural injections with contaminated methylprednisolone from a compounding pharmacy. In a new article, researchers provide details about the clinical care, deterioration, and ultimately the death of one of the index cases in this outbreak.